Dr. Ina Plettner
Notkestr. 85 (Building 15)
PHONE: +49 40 / 8998-87501
FACEBOOK: /CSSB-Centre-for-Structural- Systems-Biology
NUMBER OF EMPLOYEES: N/A
FOUNDING YEAR: 2008
A lack of knowledge of the molecular mechanisms underlying most infections presents a roadblock to the development of effective therapies. Molecular, structural and functional analysis, which uncovers and manipulates infection mechanisms, is essential for ensuring a rapid and effective response to current and future epidemics. The Centre for Structural Systems Biology (CSSB) is primarily focused on uncovering the molecular properties and ingenuities of infection mechanisms. CSSB advocates a novel approach which integrates the use of structural biology and imaging techniques with systems biology methods to attain meaningful insight into the molecular mechanisms of some of the world’s most important infections.
To conduct its structural biology research, CSSB uses the world-renowned X-ray light sources in Hamburg: the synchrotron storage ring, PETRA III, and the free electron laser, European XFEL. The beamlines of these facilities will be used in conjunction with cryo electron microscopy and a range of “omics” technologies, available at CSSB, to provide a full range of structural biology and analytical techniques.
With this unique combination of research methods and tools, CSSB endeavours to investigate a wide range of interactions involved in the infection process: from the molecular level of interactions to single cells, viral and bacterial pathogens, and ultimately entire host organisms.
CSSB is joint initiative of ten research partners from Northern Germany including three universities and seven research institutes – three Helmholtz Centres, three Leibniz Institutes and the European Molecular Biology Laboratory.
CSSB is a cooperation without its own legal personality. All partners act exclusively in their own name and on their own account.